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RNA polymerase III subunit architecture and implications for open promoter complex formation

Transcription initiation by eukaryotic RNA polymerase (Pol) III relies on the TFIIE-related subcomplex C82/34/31. Here we combine cross-linking and hydroxyl radical probing to position the C82/34/31 subcomplex around the Pol III active center cleft. The extended winged helix (WH) domains 1 and 4 of...

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Autors principals: Wu, Chih-Chien, Herzog, Franz, Jennebach, Stefan, Lin, Yu-Chun, Pai, Chih-Yu, Aebersold, Ruedi, Cramer, Patrick, Chen, Hung-Ta
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511066/
https://ncbi.nlm.nih.gov/pubmed/23132938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211665109
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