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Mapping the Protein Interaction Network for TFIIB-Related Factor Brf1 in the RNA Polymerase III Preinitiation Complex

TFIIB-related factor Brf1 is essential for RNA polymerase (Pol) III recruitment and open-promoter formation in transcription initiation. We site specifically incorporated a nonnatural amino acid cross-linker into Brf1 to map its protein interaction targets in the preinitiation complex (PIC). Our cro...

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Detalhes bibliográficos
Main Authors: Khoo, Seok-Kooi, Wu, Chih-Chien, Lin, Yu-Chun, Lee, Jin-Cheng, Chen, Hung-Ta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911497/
https://ncbi.nlm.nih.gov/pubmed/24277937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00910-13
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