Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth

Cell growth is regulated during RNA polymerase (Pol) I transcription initiation by the conserved factor Rrn3/TIF-IA in yeast/humans. Here we provide a structure–function analysis of Rrn3 based on a combination of structural biology with in vivo and in vitro functional assays. The Rrn3 crystal struct...

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Detalhes bibliográficos
Main Authors: Blattner, Claudia, Jennebach, Stefan, Herzog, Franz, Mayer, Andreas, Cheung, Alan C.M., Witte, Gregor, Lorenzen, Kristina, Hopfner, Karl-Peter, Heck, Albert J.R., Aebersold, Ruedi, Cramer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197207/
https://ncbi.nlm.nih.gov/pubmed/21940764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.17363311
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