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Total synthesis and biological evaluation of fluorinated cryptophycins

Cryptophycins are cytotoxic natural products that exhibit considerable activities even against multi-drug-resistant tumor cell lines. As fluorinated pharmaceuticals have become more and more important during the past decades, fluorine-functionalized cryptophycins were synthesized and evaluated in ce...

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Autors principals: Weiß, Christine, Bogner, Tobias, Sammet, Benedikt, Sewald, Norbert
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511040/
https://ncbi.nlm.nih.gov/pubmed/23209540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.231
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