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Total synthesis and biological evaluation of fluorinated cryptophycins
Cryptophycins are cytotoxic natural products that exhibit considerable activities even against multi-drug-resistant tumor cell lines. As fluorinated pharmaceuticals have become more and more important during the past decades, fluorine-functionalized cryptophycins were synthesized and evaluated in ce...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Beilstein-Institut
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511040/ https://ncbi.nlm.nih.gov/pubmed/23209540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.231 |
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