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Oxidative stress contributes to liver damage in a murine model of alpha-1-antitrypsin deficiency
Alpha-1-antitrypsin deficiency is a genetic disorder, resulting in the expression of misfolded mutant protein that can polymerize and accumulate in hepatocytes, leading to liver disease in some individuals. Transgenic PiZ mice are a well characterized model, which express human alpha-1-antitrypsin m...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510980/ https://ncbi.nlm.nih.gov/pubmed/23104507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2012.012106 |
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