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Characteristics of hepatocellular carcinoma in a murine model of alpha-1-antitrypsin deficiency

AIM: Individuals with homozygous (ZZ) alpha-1-antitrypsin (α1AT) deficiency are at an increased risk for liver damage, cirrhosis and hepatocellular carcinoma (HCC). The transgenic PiZ mouse, expressing the human α1AT mutant Z gene, is a valuable model for this disease. We studied PiZ mice in order t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marcus, Nancy Y., Brunt, Elizabeth M., Blomenkamp, Keith, Ali, Faiza, Rudnick, David A., Ahmad, Muneeb, Teckman, Jeffrey H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928671/
https://ncbi.nlm.nih.gov/pubmed/20618460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2010.00663.x
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