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Characteristics of hepatocellular carcinoma in a murine model of alpha-1-antitrypsin deficiency
AIM: Individuals with homozygous (ZZ) alpha-1-antitrypsin (α1AT) deficiency are at an increased risk for liver damage, cirrhosis and hepatocellular carcinoma (HCC). The transgenic PiZ mouse, expressing the human α1AT mutant Z gene, is a valuable model for this disease. We studied PiZ mice in order t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928671/ https://ncbi.nlm.nih.gov/pubmed/20618460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2010.00663.x |
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