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Hepatic progenitor cell proliferation and liver injury in alpha-1-antitrypsin deficiency

Homozygous, ZZ, alpha-1-antitrypsin (a1AT) deficiency is a common genetic liver disease, which causes liver injury and hepatocellular carcinoma (HCC) in children and adults. The a1AT mutant Z gene encodes a mutant protein which accumulates within hepatocytes leading to hepatocellular death, and a he...

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Sonraí Bibleagrafaíochta
Main Authors: Brunt, Elizabeth M, Blomenkamp, Keith, Ahmed, Muneeb, Ali, Faiza, Marcus, Nancy, Teckman, Jeffrey
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965205/
https://ncbi.nlm.nih.gov/pubmed/20890217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e3181e7ff55
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