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α-Cleavage of cellular prion protein
The cellular prion protein (PrP(C)) is subjected to various processing under physiological and pathological conditions, of which the α-cleavage within the central hydrophobic domain not only disrupts a region critical for both PrP toxicity and PrP(C) to PrP(Sc) conversion but also produces the N1 fr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510859/ https://ncbi.nlm.nih.gov/pubmed/23052041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22511 |
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