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Chromosome-specific accumulation of aneuploidy in the aging mouse brain

Chromosomal aneuploidy, the gain or loss of whole chromosomes, is a hallmark of pathological conditions and a causal factor of birth defects and cancer. A number of studies indicate that aneuploid cells are present at a high frequency in the brain of mice and humans, suggesting that mosaic aneuploid...

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Detaylı Bibliyografya
Asıl Yazarlar: Faggioli, Francesca, Wang, Tao, Vijg, Jan, Montagna, Cristina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510757/
https://ncbi.nlm.nih.gov/pubmed/22962300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds375
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