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Chromosome-specific accumulation of aneuploidy in the aging mouse brain
Chromosomal aneuploidy, the gain or loss of whole chromosomes, is a hallmark of pathological conditions and a causal factor of birth defects and cancer. A number of studies indicate that aneuploid cells are present at a high frequency in the brain of mice and humans, suggesting that mosaic aneuploid...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510757/ https://ncbi.nlm.nih.gov/pubmed/22962300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds375 |
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