Genome-wide activation of latent donor splice sites in stress and disease

Sequences that conform to the 5′ splice site (5′SS) consensus are highly abundant in mammalian introns. Most of these sequences are preceded by at least one in-frame stop codon; thus, their use for splicing would result in pre-maturely terminated aberrant mRNAs. In normally grown cells, such introni...

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Bibliografiske detaljer
Main Authors: Nevo, Yuval, Kamhi, Eyal, Jacob-Hirsch, Jasmine, Amariglio, Ninette, Rechavi, Gideon, Sperling, Joseph, Sperling, Ruth
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510495/
https://ncbi.nlm.nih.gov/pubmed/23002147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks834
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