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Genome-wide activation of latent donor splice sites in stress and disease
Sequences that conform to the 5′ splice site (5′SS) consensus are highly abundant in mammalian introns. Most of these sequences are preceded by at least one in-frame stop codon; thus, their use for splicing would result in pre-maturely terminated aberrant mRNAs. In normally grown cells, such introni...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510495/ https://ncbi.nlm.nih.gov/pubmed/23002147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks834 |
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