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The CLC-5 2Cl(−)/H(+) exchange transporter in endosomal function and Dent's disease

CLC-5 plays a critical role in the process of endocytosis in the proximal tubule of the kidney and mutations that alter protein function are the cause of Dent's I disease. In this X-linked disorder impaired reabsorption results in the wasting of calcium and low molecular weight protein to the u...

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Sonraí Bibleagrafaíochta
Main Authors: Lippiat, Jonathan D., Smith, Andrew J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510460/
https://ncbi.nlm.nih.gov/pubmed/23226131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00449
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