Reduced Ovarian Glyoxalase-I Activity by Dietary Glycotoxins and Androgen Excess: A Causative Link to Polycystic Ovarian Syndrome

Glyoxalase detoxification system composed of glyoxalase (GLO)-I and GLO-II is ubiquitously expressed and implicated in the protection against cellular damage because of cytotoxic metabolites such as advanced glycation end products (AGEs). Recently, ovarian tissue has emerged as a new target of exces...

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Autori principali: Kandaraki, Eleni, Chatzigeorgiou, Antonis, Piperi, Christina, Palioura, Eleni, Palimeri, Sotiria, Korkolopoulou, Penelope, Koutsilieris, Michael, Papavassiliou, Athanasios G
Natura: Artigo
Lingua:Inglês
Pubblicazione: ScholarOne 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510295/
https://ncbi.nlm.nih.gov/pubmed/22859292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00293
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