Advanced glycation end products interfere in luteinizing hormone and follicle stimulating hormone signaling in human granulosa KGN cells

Advanced glycation end products accumulate in the ovarian granulosa-cell layer of women with polycystic ovarian syndrome. Taken that the MAPK/ERK-pathway is a key regulator of oocyte maturation and function, consisting the main pathway used by the gonadotrophic hormones (luteinizing hormone, follicl...

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Detalles Bibliográficos
Publicado en:Exp Biol Med (Maywood)
Main Authors: Kandaraki, Eleni A, Chatzigeorgiou, Antonios, Papageorgiou, Efstathia, Piperi, Christina, Adamopoulos, Christos, Papavassiliou, Athanasios G, Koutsilieris, Michael, Diamanti-Kandarakis, Evanthia
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788153/
https://ncbi.nlm.nih.gov/pubmed/28914097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217731288
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