High Incidence of MGMT and RARβ Promoter Methylation in Primary Glioblastomas: Association with Histopathological Characteristics, Inflammatory Mediators and Clinical Outcome

Glioblastomas, the most frequent primary brain tumors in adults, are characterized by a highly aggressive, inflammatory and angiogenic phenotype. Methylation of CpG islands in cancer-related genes may serve as an epigenetic biomarker for glioblastoma diagnosis and prognosis. The aim of this study wa...

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Autors principals: Piperi, Christina, Themistocleous, Marios S, Papavassiliou, George A, Farmaki, Elena, Levidou, Georgia, Korkolopoulou, Penelope, Adamopoulos, Christos, Papavassiliou, Athanasios G
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757033/
https://ncbi.nlm.nih.gov/pubmed/19809523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00140
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