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Discovering Thiamine Transporters as Targets of Chloroquine Using a Novel Functional Genomics Strategy
Chloroquine (CQ) and other quinoline-containing antimalarials are important drugs with many therapeutic benefits as well as adverse effects. However, the molecular targets underlying most such effects are largely unknown. By taking a novel functional genomics strategy, which employs a unique combina...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510038/ https://ncbi.nlm.nih.gov/pubmed/23209439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003083 |
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