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The kinesin-14 Klp2 is negatively regulated by the SIN for proper spindle elongation and telophase nuclear positioning

In Schizosaccharomyces pombe, a late mitotic kinase pathway called the septation initiation network (SIN) triggers cytokinesis. Here we show that the SIN is also involved in regulating anaphase spindle elongation and telophase nuclear positioning via inhibition of Klp2, a minus end–directed kinesin-...

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Autori principali: Mana-Capelli, Sebastian, McLean, Janel R., Chen, Chun-Ti, Gould, Kathleen L., McCollum, Dannel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510020/
https://ncbi.nlm.nih.gov/pubmed/23087209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0532
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