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A role for metaphase spindle elongation forces in correction of merotelic kinetochore attachments

During mitosis equal segregation of chromosomes depends on proper kinetochore–microtubule attachments. Merotelic kinetochore orientation, in which a single kinetochore binds microtubules from both spindle poles [1], is a major cause of chromosome instability [2], which is commonly observed in solid...

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Detalhes bibliográficos
Main Authors: Choi, Sung Hugh, McCollum, Dannel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277651/
https://ncbi.nlm.nih.gov/pubmed/22264609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.12.022
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