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A phosphorylation dependent switch defines discrete roles for the monopolin complex in chromosome attachment and spindle elongation

BACKGROUND: It is unknown how oscillations in Cdk1 activity drive the dramatic changes in chromosome and spindle dynamics that occur at the metaphase/anaphase transition. RESULTS: We show that the S. pombe monopolin complex has distinct functions in metaphase and anaphase that are determined by the...

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Detalhes bibliográficos
Main Authors: Choi, Sung Hugh, Péli-Gulli, Marie-Pierre, Mcleod, Iain, Sarkeshik, Ali, Yates, John R., Simanis, Viesturs, McCollum, Dannel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726783/
https://ncbi.nlm.nih.gov/pubmed/19523829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.05.042
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