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Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling
The Hippo pathway controls cell proliferation, differentiation, and survival by regulating the Yes-associated protein (YAP) transcriptional coactivator in response to various stimuli, including the mechanical environment. The major YAP regulators are the LATS1/2 kinases, which phosphorylate and inhi...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6254346/ https://ncbi.nlm.nih.gov/pubmed/30266805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004187 |
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