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Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome
The Notch signaling pathway is an important contributor to the development and homeostasis of the cardiovascular system. Not surprisingly, mutations in Notch receptors and ligands have been linked to a variety of hereditary diseases that impact both the heart and the vasculature. In particular, muta...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Company of Biologists
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509736/ https://ncbi.nlm.nih.gov/pubmed/23095891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084871 |
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