Pharmacological Evaluation and Preliminary Pharmacokinetics Studies of a New Diclofenac Prodrug without Gastric Ulceration Effect

Long-term nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been associated with several adverse effects such as gastric ulceration and cardiovascular events. Among the molecular modifications strategies, the prodrug approach is a useful tool to discover new safe NSAIDs. The 1-(2,6-dichlorop...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: dos Santos, Jean Leandro, Moreira, Vanessa, Campos, Michel Leandro, Chelucci, Rafael Consolin, Barbieri, Karina Pereira, de Castro Souto, Pollyana Cristina Maggio, Matsubara, Márcio Hideki, Teixeira, Catarina, Bosquesi, Priscila Longhin, Peccinini, Rosângela Gonçalves, Chin, Chung Man
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509643/
https://ncbi.nlm.nih.gov/pubmed/23203127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131115305
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge