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Construction of a potential bivalent vaccine strain: introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain.

Shigella sonnei, an intestinal pathogen, produces a characteristic form I cell surface antigen now known to be plasmid encoded. We considered that the GalE Salmonella typhi Ty21a oral vaccine strain, highly effective against typhoid, might be modified so as to be protective also against shigellosis...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Formal, S B, Baron, L S, Kopecko, D J, Washington, O, Powell, C, Life, C A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1981
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6174449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.34.3.746-750.1981
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