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Construction of a potential bivalent vaccine strain: introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain.

Shigella sonnei, an intestinal pathogen, produces a characteristic form I cell surface antigen now known to be plasmid encoded. We considered that the GalE Salmonella typhi Ty21a oral vaccine strain, highly effective against typhoid, might be modified so as to be protective also against shigellosis...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Formal, S B, Baron, L S, Kopecko, D J, Washington, O, Powell, C, Life, C A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1981
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6174449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.34.3.746-750.1981
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