Construction of a potential bivalent vaccine strain: introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain.

Shigella sonnei, an intestinal pathogen, produces a characteristic form I cell surface antigen now known to be plasmid encoded. We considered that the GalE Salmonella typhi Ty21a oral vaccine strain, highly effective against typhoid, might be modified so as to be protective also against shigellosis...

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Détails bibliographiques
Auteurs principaux: Formal, S B, Baron, L S, Kopecko, D J, Washington, O, Powell, C, Life, C A
Format: Artigo
Langue:Inglês
Publié: 1981
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC350934/
https://ncbi.nlm.nih.gov/pubmed/6174449
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