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Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naïve T cells

Blood-borne lymphocytes home to lymph nodes by interacting with and crossing high endothelial venules (HEVs). The transendothelial migration (TEM) step is poorly understood. Autotaxin (ATX) is an ecto-enzyme that catalyzes the conversion of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA...

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Bibliografski detalji
Glavni autori: Zhang, Yafeng, Chen, Yi-Chun Maria, Krummel, Matthew F., Rosen, Steven D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509168/
https://ncbi.nlm.nih.gov/pubmed/22962684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201604
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