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Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naïve T cells
Blood-borne lymphocytes home to lymph nodes by interacting with and crossing high endothelial venules (HEVs). The transendothelial migration (TEM) step is poorly understood. Autotaxin (ATX) is an ecto-enzyme that catalyzes the conversion of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509168/ https://ncbi.nlm.nih.gov/pubmed/22962684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201604 |
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