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Elevated nuclear lamin A is permissive for granulocyte transendothelial migration but not for motility through collagen I barriers

Transendothelial migration (TEM) of lymphocytes and neutrophils is associated with the ability of their deformable nuclei to displace endothelial cytoskeletal barriers. Lamin A is a key intermediate filament component of the nuclear lamina which is downregulated during granulopoiesis. When elevated,...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Yadav, Sandeep Kumar, Feigelson, Sara W., Roncato, Francesco, Antman-Passig, Merav, Shefi, Orit, Lammerding, Jan, Alon, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504964/
https://ncbi.nlm.nih.gov/pubmed/29601096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3HI1217-488R
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