Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis

SIMPLE SUMMARY: The nucleus is the largest and stiffest organelle of tumor cells. Cancer metastasis depends on the ability of cancer cells circulating in the blood to exit blood vessels and survive in target organs. The roles of the shell (lamina) of the nucleus in cancer cell migration and survival...

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Publicat a:Cancers (Basel)
Autors principals: Roncato, Francesco, Regev, Ofer, Feigelson, Sara W., Yadav, Sandeep Kumar, Kaczmarczyk, Lukasz, Levi, Nehora, Drago-Garcia, Diana, Ovadia, Samuel, Kizner, Marina, Addadi, Yoseph, Sabino, João C., Ovadya, Yossi, de Almeida, Sérgio F., Feldmesser, Ester, Gerlitz, Gabi, Alon, Ronen
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157058/
https://ncbi.nlm.nih.gov/pubmed/34069191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102383
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