Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis

SIMPLE SUMMARY: The nucleus is the largest and stiffest organelle of tumor cells. Cancer metastasis depends on the ability of cancer cells circulating in the blood to exit blood vessels and survive in target organs. The roles of the shell (lamina) of the nucleus in cancer cell migration and survival...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Roncato, Francesco, Regev, Ofer, Feigelson, Sara W., Yadav, Sandeep Kumar, Kaczmarczyk, Lukasz, Levi, Nehora, Drago-Garcia, Diana, Ovadia, Samuel, Kizner, Marina, Addadi, Yoseph, Sabino, João C., Ovadya, Yossi, de Almeida, Sérgio F., Feldmesser, Ester, Gerlitz, Gabi, Alon, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157058/
https://ncbi.nlm.nih.gov/pubmed/34069191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102383
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