Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the present work, we explored whether a RASSL of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2012
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509056/
https://ncbi.nlm.nih.gov/pubmed/22919070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-213314
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker