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Facilitators and Impediments of the Pluripotency Reprogramming Factors’ Initial Engagement with the Genome

The ectopic expression of transcription factors can reprogram cell fate, yet it is unknown how the initial binding of factors to the genome relates functionally to the binding seen in the minority of cells that become reprogrammed. We report a map of Oct4, Sox2, Klf4, and c-Myc (O, S, K, and M) on t...

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Bibliografische gegevens
Hoofdauteurs: Soufi, Abdenour, Donahue, Greg, Zaret, Kenneth S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508134/
https://ncbi.nlm.nih.gov/pubmed/23159369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.09.045
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