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Plasma Factors during Chronic HIV-1 Infection Impair IL-12 Secretion by Myeloid Dendritic Cells via a Virus-Independent Pathway

OBJECTIVE: Myeloid dendritic cell (mDC) dysfunction during HIV infection may hinder the formation of both innate and adaptive immune responses and contribute to pathogenesis. Our objective was to determine whether circulating factors during chronic HIV infection impair mDC function with respect to s...

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Detalhes bibliográficos
Main Authors: Miller, Elizabeth A., Spadaccia, Meredith R., O’Brien, Meagan P., Rolnitzky, Linda, Sabado, Rachel, Manches, Olivier, Frleta, Davor, Bhardwaj, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508089/
https://ncbi.nlm.nih.gov/pubmed/22902724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31826afbce
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