Dose-dependent effects of small-molecule antagonists on the genomic landscape of androgen receptor binding

BACKGROUND: The androgen receptor plays a critical role throughout the progression of prostate cancer and is an important drug target for this disease. While chromatin immunoprecipitation coupled with massively parallel sequencing (ChIP-Seq) is becoming an essential tool for studying transcription a...

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Main Authors: Zhu, Zhou, Shi, Manli, Hu, Wenyue, Estrella, Heather, Engebretsen, Jon, Nichols, Tim, Briere, David, Hosea, Natilie, Los, Gerrit, Rejto, Paul A, Fanjul, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507642/
https://ncbi.nlm.nih.gov/pubmed/22849360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-355
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