Understanding the origins of UV-induced recombination through manipulation of sister chromatid cohesion

Ultraviolet light (UV) can provoke genome instability, partly through its ability to induce homologous recombination (HR). However, the mechanism(s) of UV-induced recombination is poorly understood. Although double-strand breaks (DSBs) have been invoked, there is little evidence for their generation...

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Detaylı Bibliyografya
Asıl Yazarlar: Covo, Shay, Ma, Wenjian, Westmoreland, James W., Gordenin, Dmitry A., Resnick, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Perspective
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507489/
https://ncbi.nlm.nih.gov/pubmed/22987150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21945
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