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The Sister Chromatid Cohesion Pathway Suppresses Multiple Chromosome Gain and Chromosome Amplification

Gain or loss of chromosomes resulting in aneuploidy can be important factors in cancer and adaptive evolution. Although chromosome gain is a frequent event in eukaryotes, there is limited information on its genetic control. Here we measured the rates of chromosome gain in wild-type yeast and sister...

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Detalhes bibliográficos
Main Authors: Covo, Shay, Puccia, Christopher M., Argueso, Juan Lucas, Gordenin, Dmitry A., Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914611/
https://ncbi.nlm.nih.gov/pubmed/24298060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.159202
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