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Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes
Double-strand break (DSB) repair through homologous recombination (HR) is an evolutionarily conserved process that is generally error-free. The risk to genome stability posed by nonallelic recombination or loss-of-heterozygosity could be reduced by confining HR to sister chromatids, thereby preventi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895640/ https://ncbi.nlm.nih.gov/pubmed/20617204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001006 |
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