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Cohesin Is Limiting for the Suppression of DNA Damage–Induced Recombination between Homologous Chromosomes

Double-strand break (DSB) repair through homologous recombination (HR) is an evolutionarily conserved process that is generally error-free. The risk to genome stability posed by nonallelic recombination or loss-of-heterozygosity could be reduced by confining HR to sister chromatids, thereby preventi...

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Detalhes bibliográficos
Main Authors: Covo, Shay, Westmoreland, James W., Gordenin, Dmitry A., Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895640/
https://ncbi.nlm.nih.gov/pubmed/20617204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001006
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