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MicroRNAs Regulate Renal Tubule Maturation through Modulation of Pkd1

MicroRNAs (miRNAs) contribute to the regulation of early kidney development, but their role during later stages of renal tubule maturation is not well understood. Here, we found that ablation of the miRNA-processing enzyme Dicer from maturing renal tubules produces tubular and glomerular cysts in mi...

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Hlavní autoři: Patel, Vishal, Hajarnis, Sachin, Williams, Darren, Hunter, Ryan, Huynh, Donovan, Igarashi, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507362/
https://ncbi.nlm.nih.gov/pubmed/23138483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012030321
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