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Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis

microRNAs (miRNAs) are sequence-specific inhibitors of post-transcriptional gene expression. The physiologic function of these noncoding RNAs in postnatal renal tubules still remains unclear. Surprisingly, they appear to be dispensable for mammalian proximal tubule (PT) function. Here, we examined t...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Hajarnis, Sachin, Yheskel, Matanel, Williams, Darren, Brefort, Thomas, Glaudemans, Bob, Debaix, Huguette, Baum, Michel, Devuyst, Olivier, Patel, Vishal
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791084/
https://ncbi.nlm.nih.gov/pubmed/29021386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030334
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