Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis

microRNAs (miRNAs) are sequence-specific inhibitors of post-transcriptional gene expression. The physiologic function of these noncoding RNAs in postnatal renal tubules still remains unclear. Surprisingly, they appear to be dispensable for mammalian proximal tubule (PT) function. Here, we examined t...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Hajarnis, Sachin, Yheskel, Matanel, Williams, Darren, Brefort, Thomas, Glaudemans, Bob, Debaix, Huguette, Baum, Michel, Devuyst, Olivier, Patel, Vishal
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2018
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791084/
https://ncbi.nlm.nih.gov/pubmed/29021386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030334
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