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Heme/Copper Assembly Mediated Nitrite and Nitric Oxide Interconversion

The heme(a3)/Cu(B) active site of cytochrome c oxidase is responsible for cellular nitrite reduction to nitric oxide; the same center can return NO to the nitrite pool via oxidative chemistry. Here, we show that a partially reduced heme/Cu assembly reduces NO(2)(−) ion producing nitric oxide. The he...

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Main Authors: Hematian, Shabnam, Siegler, Maxime A., Karlin, Kenneth D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507325/
https://ncbi.nlm.nih.gov/pubmed/23130610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3083818
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