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Heme/Copper Assembly Mediated Nitrite and Nitric Oxide Interconversion
The heme(a3)/Cu(B) active site of cytochrome c oxidase is responsible for cellular nitrite reduction to nitric oxide; the same center can return NO to the nitrite pool via oxidative chemistry. Here, we show that a partially reduced heme/Cu assembly reduces NO(2)(−) ion producing nitric oxide. The he...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3507325/ https://ncbi.nlm.nih.gov/pubmed/23130610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3083818 |
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