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UVSSA and USP7: new players regulating transcription-coupled nucleotide excision repair in human cells

Transcription-coupled nucleotide excision repair (TC-NER) specifically removes DNA damage located in actively transcribed genes. Defects in TC-NER are associated with several human disorders, including Cockayne syndrome (CS) and ultraviolet (UV)-sensitive syndrome (UV(S)S). Using exome sequencing, a...

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Autore principale: Sarasin, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506910/
https://ncbi.nlm.nih.gov/pubmed/22621766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm343
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