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Novel Functions of the Phosphatase SHP2 in the DNA Replication and Damage Checkpoints

Replication stress- and DNA damage-induced cell cycle checkpoints are critical for maintaining genome stability. To identify protein phosphatases involved in the activation and maintenance of the checkpoints, we have carried out RNA interference-based screens with a human phosphatome shRNA library....

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Autors principals: Tsang, Yiu Huen, Han, Xianxian, Man, Wing Yu, Lee, Nelson, Poon, Randy Y. C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506573/
https://ncbi.nlm.nih.gov/pubmed/23189174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049943
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