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Novel Functions of the Phosphatase SHP2 in the DNA Replication and Damage Checkpoints

Replication stress- and DNA damage-induced cell cycle checkpoints are critical for maintaining genome stability. To identify protein phosphatases involved in the activation and maintenance of the checkpoints, we have carried out RNA interference-based screens with a human phosphatome shRNA library....

詳細記述

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書誌詳細
主要な著者: Tsang, Yiu Huen, Han, Xianxian, Man, Wing Yu, Lee, Nelson, Poon, Randy Y. C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506573/
https://ncbi.nlm.nih.gov/pubmed/23189174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049943
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