A phase I study of bortezomib and temozolomide in patients with advanced solid tumors

PURPOSE: The primary objective was to determine the maximum tolerated doses (MTDs) of the combination of bortezomib and temozolomide in patients with solid tumors. The secondary objective was to evaluate the pharmacokinetics (PK) of bortezomib with and without concurrent hepatic enzyme-inducing anti...

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Detalhes bibliográficos
Main Authors: Portnow, J., Frankel, P., Koehler, S., Twardowski, P., Shibata, S., Martel, C., Morgan, R., Cristea, M., Chow, W., Lim, D., Chung, V., Reckamp, K., Leong, L., Synold, T. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506384/
https://ncbi.nlm.nih.gov/pubmed/21850464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1721-x
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