Interleukin-6 Production in CD40-Engaged Fibrocytes in Thyroid-Associated Ophthalmopathy: Involvement of Akt and NF-κB

PURPOSE. CD40–CD40 ligand (CD40L) interactions appear to play pathogenic roles in autoimmune disease. Here we quantify CD40 expression on fibrocytes, circulating, and bone marrow–derived progenitor cells. The functional consequences of CD40 ligation are determined since these may promote tissue remo...

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Detaylı Bibliyografya
Asıl Yazarlar: Gillespie, Erin F., Raychaudhuri, Nupur, Papageorgiou, Konstantinos I., Atkins, Stephen J., Lu, Ying, Charara, Laya K., Mester, Tünde, Smith, Terry J., Douglas, Raymond S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506052/
https://ncbi.nlm.nih.gov/pubmed/23092922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9861
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