Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats

BACKGROUND: Levodopa is the gold standard in the treatment of Parkinson’s disease (PD). However, long-term levodopa replacement therapy is accompanied by abnormal involuntary movements (AIMs), known as levodopa-induced dyskinesia (LID). Until now, the precise mechanisms of LID were only partially un...

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Detalhes bibliográficos
Main Authors: Yang, Xinxin, Chen, Yinghui, Hong, Xiaoyun, Wu, Na, Song, Lu, Yuan, Weien, Liu, Zhenguo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506046/
https://ncbi.nlm.nih.gov/pubmed/23185117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S38008
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