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Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

Astrocytes are the most abundant cell type in the brain and play a critical role in maintaining healthy nervous tissue. In Alzheimer's disease (AD) and most other neurodegenerative disorders, many astrocytes convert to a chronically “activated” phenotype characterized by morphologic and biochem...

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Bibliografiske detaljer
Main Authors: Furman, Jennifer L., Sama, Diana M., Gant, John C., Beckett, Tina L., Murphy, M. Paul, Bachstetter, Adam D., Van Eldik, Linda J., Norris, Christopher M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506017/
https://ncbi.nlm.nih.gov/pubmed/23152597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2323-12.2012
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