Differential Roles of Insulin Receptor Substrates in Brown Adipocyte Differentiation

Insulin promotes adipocyte differentiation via a complex signaling network involving multiple insulin receptor substrates (IRSs). In cultured brown preadipocytes, expression of IRS-1 and IRS-2 mRNAs and proteins was at relatively high levels before and after differentiation into mature fat cells, wh...

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Bibliographic Details
Main Authors: Tseng, Yu-Hua, Kriauciunas, Kristina M., Kokkotou, Efi, Kahn, C. Ronald
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC350563/
https://ncbi.nlm.nih.gov/pubmed/14966273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1918-1929.2004
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