Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

Increased afterload results in ‘pathological’ cardiac hypertrophy, the most important risk factor for the development of heart failure. Current in vitro models fall short in deciphering the mechanisms of hypertrophy induced by afterload enhancement. The aim of this study was to develop an experiment...

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Detalhes bibliográficos
Main Authors: Hirt, Marc N., Sörensen, Nils A., Bartholdt, Lena M., Boeddinghaus, Jasper, Schaaf, Sebastian, Eder, Alexandra, Vollert, Ingra, Stöhr, Andrea, Schulze, Thomas, Witten, Anika, Stoll, Monika, Hansen, Arne, Eschenhagen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505530/
https://ncbi.nlm.nih.gov/pubmed/23099820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0307-z
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