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Selective delivery of interleukine-1 receptor antagonist to inflamed joint by albumin fusion

BACKGROUND: Interleukin-1 receptor antagonist, a cytokine that is highly therapeutic to rheumatoid arthritis and several other inflammatory diseases, exhibits rapid blood clearance and poor retention time on the target in clinical application due to its small size and lack of specificity to target t...

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Hlavní autoři: Liu, Mengyuan, Huang, Yi, Hu, Lei, Liu, Guoping, Hu, Xueping, Liu, Dongxu, Yang, Xiaosong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505484/
https://ncbi.nlm.nih.gov/pubmed/23006786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-12-68
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